Archives 2021
Scientific events
Folles souris 2021
Nous avons le plaisir de vous annoncer la tenue de la 4ème édition du colloque « Les Folles Souris Nantaises », qui aura lieu dans le grand amphithéâtre de la faculté de Pharmacie (rue Bias), le 30 Novembre prochain (de 9.00 à 17.00). Le programme avec les horaires est téléchargeable ici. L'inscription est gratuite mais obligatoire (places limitées) avant le 02 Novembre 2021/> Ce colloque s'adresse aux chercheurs statutaires, post-doctorants, aux doctorants, et tout le personnel des services supports concernés. La participation à cette journée compte pour la formation continue en expérimentation animale.
Devstem
The DEVSTEM meeting took place on October 5th, 2021 at 10.00 am (Room 1 - Dental Faculty). Presentations of N. Provin & C. Harly
Fete de la Science 2021
As every year, the RMeS laboratory participated in the Science Festival. This year, the national theme was "the emotion of discovery". This national event took place from October 1 to 11.
New funding by IFRO for HOTSPOT (Heterogeneity of OsteoclasT precursorS in PeriodOnTitis)
The REGOS team of the INSERM UMR_S 1229 RMeS laboratory is pleased to announce that the HOTSPOT project has been funding by the IFRO (Institut Français pour la Recherche Odontologique) 2021 grant. HOTSPOT will be coordinated by Alexandra Cloitre (INSERM UMR_S 1229 RMeS) and will be carried out with Frederic Blanchard (INSERM UMR_S 1238, Phy-OS) with the support of Emilie Hascoët, Julien De Lima and Philippe Lesclous. HOTSPOT aims to identify and characterize inflammatory osteoclast precursors in gingiva from periodontitis patients. These cells may contribute to the alveolar bone loss and, in fine to dental loss associated to periodontitis.
Award for J. Guicheux
STEP team is happy to announce that Jerome Guicheux recently received the « Jean Bayle-Lespiteau » Achievement Award from the «Fondation de l’Avenir » (FDA). We are very grateful to FDA board and those who nominated him. STEP team has worked with this health research and innovation dedicated foundation for almost 20 years. This Award is a high honor and also a tribute to the alumni and current members of the STEP team that contribute to make our research a source of hope for patients with joint diseases. A video presenting the activities of the STEP team was filmed on this occasion.
Selection of M.A. Boutet in program ATIP-Avenir 2021
Marie-Astrid Boutet, currently a postdoc in Claire Vinatier’s group (STEP team), has been selected for the competitive program Inserm/CNRS ATIP-Avenir 2021. Her StratOA group will investigate the diversity of synovial macrophages in osteoarthritis. Congratulations Marie-Astrid !
Devstem
The DEVSTEM meeting took place on July 6, 2021 in Amphi Landais (Dental Faculty) & via visioconference. Presentations of Jean-baptiste Dupont & Valentin Francois-Campion et Jérome Jullien. Keywords : H2AK119Ub, sperm, early embryogenesis, transcriptomics, epigenetics, polycomb repressive comple
New fundings from SFR
SFR (Société Française de Rhumatologie) has decided to fund 2 RMeS projects : METABONE, led by Dr Sarah Beck-Cormier which aims to understand the role of the PiT2/SLC20A2 protein in bone pathologies associated with metabolic abnormalities & SPHERODISC led by Dr Anne CAMUS. This project aims to characterize the cellular interactions regulating disc tissue homeostasis in a human stem cell-derived organoid model. These investigations will contribute to the discovery of symptom-modifying factors or new therapeutic targets and in the long term to the emergence of innovative treatments that should bring strong benefits to patient with back pain and age-related intervertebral disc diseases.
Interview of J. Guicheux on the channel "Sport en France"
Jérôme Guicheux participated on February 12 to a program on the channel "Sport en France". He spoke on the programme "Sport, Health & Technology" and answered very general questions about low back pain and research carried out by RMeS
Nuit Blanche des Chercheurs (Feb 11th, 2021)
RMeS has participated in the "Nuit Blanche des Chercheurs" by offering a workshop on regenerative medicine. You can replay it on the link : Workshops (from 1h34)
The DEVSTEM meeting took place on March 16, 2021 at 10.00 am via visioconference. Presentations of Lily Paillat & Nicolas Vedrenne
RegenHU's latest 3D bioprinter is in the RMeS lab!
Can't wait to explore the possibilities of this technological gem for all our bioprinting applications!
J. Clouet has received a grant from the "Fondation d'Entreprise Grand Ouest"
We are pleased to announce that Johann CLOUET, PU-PH at RMeS, has received a €5,000 grant from the "Fondation d'Entreprise Grand Ouest" for his NEMESIS project: "Nanoparticles Engineering for MiRNA Encapsulation in Skeletal Innovative Science".
P. Weiss becomes a Fellow of Biomaterials Science and Engineering (FBSE)
P. Weiss is really proud to become a Fellow of Biomaterials Science and Engineering (FBSE). He thanks the World Biomaterial organization, the European Society for Biomaterials, the French society Biomat and the colleagues who nominated him. It will be his pleasure to help the community with this new mission..
EVENDO project
The REGOS team of the Inserm U1229-RMeS laboratory is pleased to announce that the EVENDO project won the European Society of Endodontics (ESE) Annual Research Grant 2020. The EVENDO project will be hosted in the research laboratory Inserm U1229 and will be coordinated by Alexis Gaudin with the support of Angelique Galvani, Valerie Geoffroy, Davy Aubeux, Solène Tessier, Pierre Weiss, and Fabienne Pérez. The specific goal of “EVENDO” project is to carry out a detailed characterization of extracellular vesicles derived from primed dental mesenchymal stem cells (pDMSC-EVs) to investigate their involvement as modulators of mesenchymal stem cells anti-inflammatory effects inducing macrophage polarization and to explore whether these pDMSC-EVs may become a valuable tool for promoting dental pulp regeneration.
Media / Press
Régénérer le squelette : un biocomposite répare les pertes osseuses
Interview of P. Weiss
Sciences et Vie
Anoucement
New funding by FRM for DISCAFF project
The STEP team is pleased to announce the funding of the DISCAFF project in response to the 2021 call for proposals "Reparative medicine" from the French Medical Research Foundation (FRM). DISCAFF is a collaborative research project that will be coordinated by Jerome Guicheux and Catherine Le Visage (INSERM UMRS 1229-RMeS). DISCAFF will aim to develop new bio-inspired materials for intervertebral disc repair in partnership with the CNRS UMR 5247 laboratory (Montpellier, X. Garric) and the Institute of Orthopaedic Research and Biomechanics (Ulm, Germany, H-J Wilke). DISCAFF will be supported by the FRM for 3 years.
New funding by ANR for PARKA
The STEP team is pleased to announce the recent funding of the PARKA proposal as an ANR collaborative research project. PARKA will be coordinated by Laurent Beck (RMeS), with Marie-Hélène Lafage-Proust (Sainbiose Inserm UMR1059, St Etienne), David Magne (ICBMS CNRS 5246, Lyon) and Denis Fouque (Carmen Inserm UMR1060, Lyon) as partners. The aim is to decipher the mechanism of action of phosphate in the development of vascular calcification in the context of chronic kidney disease, with the ultimate goal to identify putative therapeutic targets able to counteract its deleterious effects in humans. To this end, our consortium proposes an integrated approach encompassing the entire spectrum of phosphate regulation (from its intestinal absorption to its local vascular effects and systemic role) and the transfer of our findings in mice to humans.
New funding by ANR for IDEAL-3D
The REGOS team of the Inserm U1229-RMeS laboratory is pleased to announce the recent funding of the IDEAL-3D proposal as an ANR collaborative research project. IDEAL-3D will be coordinated by Sylvain Catros (BIOTIS, Bordeaux) with Alexandra Cloitre and Philippe Lesclous (RMeS), with Lise Chagot (BIOTIS, Bordeaux), with Makoto Miyara (CIMI, Paris) and Nicolas Courtois (ANTHOGYR, Sallanches). The aim of this project is to fabricate and evaluate an in vitro 3D model representative of the processes of osseointegration and soft tissue integration of dental implants, using Bioprinting techniques, in order to serve as a reliable and reproducible platform for research in implant dentistry.
People events
HDR of Gildas Rethoré
Gildas defended his HDR on December 7th, 2021 at 2.00 pm
Marielle Garcia
Marielle is trainee assistant engineer. She will work on the evaluation of the activity of extracellular vesicles on the cells of the intervertebral disc.
She joined our unit on September 1st 2021
Her supervisors are Catherine Le Visage & Paul Humbert
Arnaud Eyraud
Arnaud is Assistant Engineer. He will be the administrative coordinator and human resources of the unit
He joined our unit on July 1th 2021
His supervisor is Jérôme Guicheux
Marie-Astrid Boutet
Marie-Astrid is post-doc. She will work on the understanding of the pathogenic role of synovial macrophages during osteoarthritis
She joined our unit on February 15th 2021
Her supervisors are Claire Vinatier & Jérôme Guicheux
Congratulations to Nora Bouhsina for her PhD Defense !
Nora defended her thesis on September 21th, 2021 at 2.00 pm (Amphi Ricordeau)
Titre: Contribution au développement de nouvelles techniques d’imagerie pour la détection précoce de la dégénérescence discale dans un contexte de médecine régénératrice
Directeur de thèse: Johann Clouet - Co-directeur : Marion Fusellier
Justine Parisse
Justine is trainee assistant engineer. She will work on the encapsulation of extracellular vesicles (EVs)
She joined our unit on September 1st 2021
Her supervisors are Pierre Guihard and Pierre Weiss
Prof. Olivier Gauthier elected Trustee of the AO Foundation
Professor Olivier Gauthier has been elected "Trustee" of the AO Foundation, a prestigious organization in the world of human and veterinary orthopedics. Congratulations Olivier!
Lena Guyon
Lena is Engineer. She will work on the BILIPOX and LFC projects
She joined our unit on August 16th 2021
Her supervisors are Alexis Gaudin et Pierre Weiss
Admission of Vianney Delplace for a permanent researcher position at Inserm
RMeS lab is pleased to announce the admission of V. Delplace to the competitive recruitement for a permanent researcher position at Inserm. Bringing in a strong expertise in chemistry and biomedical engineering, he will develop innovative bioprinting technologies for joint-on-a-chip design and novel biomaterial-assisted cell therapy strategies for osteoarthritis treatment. Congratulations Vianney!
Maud Viallon
Maud is post-doc. She will work on a multidisciplinary project whose central theme is biopolymers and biomaterials with application in medicine/health.
She joined our unit on February 1, 2021
Her supervisor is Pierre Weiss
Emmaëlle Carrot
Emmaëlle is a M2 Student. She will work on the bioprinting of an intervertebral disc.
She joined our unit on February 1, 2021
Her supervisor is Catherine Le Visage
James Muncey
James is a M2 Student. He will work on the development and biological characterization of a bio-printed synovia model as a basis for the design of mini-joint and in vitro osteoarthritis models
He joined our unit on February 1, 2021
His supervisor is Vianney Delplace
Congratulations to Benoit Bodic for his PhD Defense !
Benoit defended his thesis on March 24th, 2021 at 2.00 pm
Amélioration des propriétés anti-arthrosiques des MSC: développement de nouvelles méthodes
Directeur de thèse: J. Guicheux - Co-directeur : F. Djouad (IRMB, Montpellier)
PhD Defense of Alban Fouasson-Chailloux
Alban defended his thesis on April 9th, 2021 at 2.00 pm (salle de conférence de l'hôpital st Jacques)
Title: Arthropathies et Analyse du Mouvement - Arthrose et Arthropathie Hémophilique
Directeur de thèse: Y. Maugars - Co-directeur : F. Rannou
Congratulations to Florent Autrusseau for his HDR !
Florent defended his HDR on February 3rd, 2021 at 2.00 pm
Titre: Perception des images numériques, de la sécurité des contenus à l’analyse des images médicales
Ségolène Reiss
Maëva Dutilleul
Julie Warin
Paul Humbert
Gabriel Rouau
Samuel Mandin
Jérémy Brogard