plos one
Radiographic evaluation of percutaneous transfacial wiring versus open internal fixation for surgical treatment of unstable zygomatic bone fractures

Giran G, Paré A, Croisé B, Koudougou C, Mercier JM, Laure B, Corre P, Bertin H

PLoS One. 2019 Aug 15;14(8):e0220913 - Download full text

Int J of Cardio
Antibiotic prophylaxis of infective endocarditis in patients with predisposing cardiac conditions: French cardiologists' implementation of current guidelines

Cloitre A, Lesclous P, Trochu Q, Selton-Suty C, Boutoille D, Le Tourneau T, Delahaye F, Thomas D, Iung B, Gaudin A, Duval X, Trochu JN

Int J Cardiol. 2019 Jul 12 - Download full text

Heart Vessels
Sequential coronary bifurcation revascularization with the Xposition S™ self-apposing stent: a comparative fractal bench study

Dérimay F, Maillard L, Rioufol G, Souteyrand G, Aminian A, Veziers J, Guerin P, Finet G

Heart Vessels. 2019 Jun 27 -

Human Enriched Serum Following Hydrolysed Collagen Absorption Modulates Bone Cell Activity: from Bedside to Bench and Vice Versa

Wauquier F, Daneault A, Granel H, Prawitt J, Fabien Soulé V, Berger J, Pereira B, Guicheux J, Rochefort GY, Meunier N, Blot A, Wittrant Y

Nutrients. 2019 May 31;11(6) - Download full text


ANRNew funding of ANR JCJC 2019

The REGOS team of the INSERM U1229-RMeS laboratory is pleased to announce the success of the BILIPOX project in ANR JCJC 2019. The laboratory will receive a grant of 305k€ for 3 years to hire dedicated staff (Engineer and technician). The BILIPOX project will be coordinated by Alexis Gaudin and will be carried out in collaboration with Christophe Blanquart (CRCINA, INSERM UMR 1232), Philippe Legrand (UMR 5253 CNRS- UM-ENSCM), Jeff Johnson (Cayman Chemical Company) and Stéphane Simon (University Paris Diderot (Paris VII). The specific goal of this project is to evaluate the potential benefits of a new biphasic microgel as lipoxin A4 (LXA4) delivery system for tissue engineering (pulp and periodontal tissue). The results of BILIPOX may provide a better understanding of microgels/macrophage interaction. This would be an important milestone for hydrogels modular strategy that open a new way to design and to multi-functionalize drug delivery systems.

nextNew funding of NExT

The STEP team of the INSERM U1229-RMeS laboratory is pleased to announce the success of the SHELBY project in phase 2 of the NExT IIP (Internal interdisciplinary projects) call of proposals. The laboratory will receive a grant of 140 k€ for 3 years to hire dedicated staff (PhD student or engineer). The SHELBY project will be coordinated by Catherine Le Visage and will be carried out in collaboration with Denis Renard (INRA BIA) and Arnaud Teissier (CEISAM, CNRS). The objectives of this project are to develop innovative hydrogels for stem cell encapsulation by lithography, with particular application to cell therapy of disc or peripheral osteoarthritis.

Prix GiuliaJFBTM Award for Giulia Frangi

Congratulations to Giulia Frangi who obtained the JFBTM Award for the best oral presentation "Young Researcher" for her talk entitled : "Altered bone marrow adiposity in pit2-deficient mice" (Boulogne/mer, June 5-7, 2019)

sfrNew funding of SFR

SFR (Société Française de Rhumatologie) has decided to finance : REVAGO, headed by Angélique Galvani & Valérie Geoffroy. The aim of the REVAGO project is to explore an innovative communication network between bone cells based on extracellular vesicles (EVs), and elucidate its role during bone aging.

Workshops & symposia

Termis Meeting, 27th-31st May 2019, Rhodes, Greece

Several members of our unit organize symposia during this conference :

  • Vianney Delplace & Pierre Weiss : "From innovative hydrogel chemistry to musculoskeletal regeneration approaches"
  • Catherine Le Visage & Valérie Geoffroy: "MSC-derived Extracellular Vesicles: from production, engineering and administration challenges to bone tissue regenerative therapies"
  • Jérome Guicheux & Marianna Trifonnidou: Advanced therapies of the future for spinal regeneration: The H2020 European iPSpine project
  • Claire Vinatier & Anne Desrieux : "New frontiers in osteoarthritis treatment: prospects for stem cells, extracellular vesicles and biomaterials-assisted cell therapies"


Makarand V. RisbudMakarand V. Risbud, Ph.D

pH Regulation and its Metabolic Consequences in Intervertebral Disc Health and Disease

Thomas Jefferson University
July 1, 2019, 11h00 - Amphi D. Escande(IRS-UN)


Dominique PiolettiDominique Pioletti, PhD

The role of dissipation in developing hydrogels with increased mechanical and mechanobiological properties

Laboratory of Biomechanical Orthopedics,EPFL
April 24th, 2019, 11h00 - Amphi Ricordeau (Dental Faculty)


RMeS in the spotlight

talk ambassy1st France-USA Stem cell Symposium, Los Angeles 2019

Jérôme Guicheux has been invited to give a talk on "Stem cells and biomaterials for spinal joint regenerative medicine : from biologically inspired concepts to clinical transfer" at the 1st France-USA Stem cell symposium that took place in Los Angeles (June 25th, 2019)

intervention rouenSNMS, Rouen 2019

Jérôme Guicheux has been invited to give a talk on stem cells and regenerative medicine: "Cellules souches et médecine régénératrice des articulations : la route est-elle encore longue ?"at the SNMS congress that took place in Rouen (June 8th, 2019)

Laurent Beck ECTSECTS, Hongrie 2019

Laurent Beck was invited to give a basic science update on phosphate sensing and to present Nina Bon's recently published work on this subject at the ECTS congress that took place in Budapest (10-15 may 2019)

New members

Caroline ChariauCaroline Chariau

Caroline (ass. ing. ) will work on Notochordal differentiation and stem cell-based therapy for intervertebral disc degeneration (H2020 iPSpine project; agreement No 825925)

She joined our unit on March 11th 2019
Her supervisor is Anne Camus

Nicolas VedrenneNicolas Védrenne

Nicolas is post-doctoral researcher
He will work on Notochordal differentiation and stem cell-based therapy for intervertebral disc degeneration (H2020 iPSpine project)

He joined our unit on March 11th 2019
His supervisor is Anne Camus

HassanHassan Kaafarani

Hassan is a M2 student.
He will work on REGOMIR project

He joined our unit on Feb. 20th 2019
His supervisor is Valérie Geoffroy

Pierre-Guillaume PiriouPierre-Guillaume Piriou

Pierre-Guillaume is a M2 student.
He will work on the evaluation of the biomechanical characteristics of coronary stents and their performance in simple model and bifurcation model.

He joined our unit on Jan. 28th 2019
His supervisors are Thierry Rouillon & Fabienne Jordana

PhD defense & HDR

Leslie FrapinPhD Defense of Leslie Frapin

Leslie will defend her thesis on December 11, 2019, at 14.00 pm (Amphi D. Escande)

Ingénierie tissulaire du disque intervertébral: Développement d'un système à libération séquentielle de facteurs biologiques pour la réparation endogène du disque intervertébral humain

Directeur de thèse: C. Le Visage - Co-directeur : J. Guicheux - Co-encadrant : J. Clouet

Photo thèse ArnaudPhD Defense of Arnaud Paré

Arnaud defended his thesis on July 11, 2019, at 14.00 pm (Amphi Ricordeau)

Rôle de l'apport du dioxygène dans la régénération osseuse en zone ischémique: application aux défauts osseux mandibulaires interrupteurs

Directeur de thèse: P. Corre - Co-directeur : Olivier Gauthier

KillianPhD Defense of Killian Flégeau

Killian defended his thesis on April 24, 2019, at 14.00 pm

Développement et caractérisation d'hydrogels d'acide hyaluronique auto-réticulants injectables en ingénierie tissulaire du squelette

Directeur de thèse: P. Weiss - Co-directeur : Hélène Gautier

And among other things...

General Assembly 2018

RMeS General Assemby (Campus Gavy - St Nazaire) -
May 14th, 2018

Photo Fête de Noël
Christmas Party RMeS ! December 18th, 2017

Olympiades RMES

The 2nd Edition of the RMeS "Olympiades" has taken place on Sept. 18th, 2017. 4 teams have met in good spirits. Thanks to all the participants!