Publications

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Shoulder Isokinetic Strength Deficit in Patients with Neurogenic Thoracic Outlet Syndrome

P. Daley, G. Pomares, P. Menu, G. Gadbled, M. Dauty, A. Fouasson-Chailloux

Life (Basel) . 2021 Aug 7;11(8):798. - Download full text

ecm
Correlation between magnetic resonance, X-ray imaging alterations and histological changes in an ovine model of age-related disc degeneration

N. Bouhsina, C. Decante, J-B. Hardel, S. Madec, J. Abadie, A Hamel, C. Le Visage, J. Lesoeur, J. Guicheux, J. Clouet, M. Fusellier

Eur Cell Mater . 2021 Sep 24 -
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Announcements

fra New funding by FRM for DISCAFF project

The STEP team is pleased to announce the funding of the DISCAFF project in response to the 2021 call for proposals "Reparative medicine" from the French Medical Research Foundation (FRM). DISCAFF is a collaborative research project that will be coordinated by by Jerome Guicheux and Catherine Le Visage (INSERM UMRS 1229-RMeS). DISCAFF will aim to develop new bio-inspired materials for intervertebral disc repair in partnership with the CNRS UMR 5247 laboratory (Montpellier, X. Garric) and the Institute of Orthopaedic Research and Biomechanics (Ulm, Germany, H-J Wilke). DISCAFF will be supported by the FRM for 3 years.

ANR New funding by ANR for PARKA

The STEP team of the Inserm UMR1229 RMeS Lab is pleased to announce the recent funding of the PARKA proposal as an ANR collaborative research project. PARKA will be coordinated by Laurent Beck (RMeS), with Marie-Hélène Lafage-Proust (Sainbiose Inserm UMR1059, St Etienne), David Magne (ICBMS CNRS 5246, Lyon) and Denis Fouque (Carmen Inserm UMR1060, Lyon) as partners. The aim of this project is to decipher the mechanism of action of phosphate in the development of vascular calcification in the context of chronic kidney disease, with the ultimate goal to identify putative therapeutic targets able to counteract its deleterious effects in humans. To this end, our consortium proposes an integrated approach encompassing the entire spectrum of phosphate regulation (from its intestinal absorption to its local vascular effects and systemic role) and the transfer of our findings in mice to humans.

ANR New funding by ANR for IDEAL-3D

The REGOS team of the Inserm U1229-RMeS laboratory is pleased to announce the recent funding of the IDEAL-3D proposal as an ANR collaborative research project. IDEAL-3D will be coordinated by Sylvain Catros (BIOTIS, Bordeaux) with Alexandra Cloitre and Philippe Lesclous (RMeS), with Lise Chagot (BIOTIS, Bordeaux), with Makoto Miyara (CIMI, Paris) and Nicolas Courtois (ANTHOGYR, Sallanches). The aim of this project is to fabricate and evaluate an in vitro 3D model representative of the processes of osseointegration and soft tissue integration of dental implants, using Bioprinting techniques, in order to serve as a reliable and reproducible platform for research in implant dentistry.

ANR New funding by ANR for CREABONE

The REGOS team of the Inserm U1229-RMeS laboratory is pleased to announce the recent funding of the CREABONE proposal as an ANR collaborative research project. CREABONE will be coordinated by Federico Perche and Chantal Pichon (UPR 4301 CNRS, CBM, Orléans) with Pierre Weiss and Valérie Geoffroy (RMeS) and Delphine Logeart-Avramoglou (B3OA - CNRS UMR705, Inserm U1271). The CREABONE project proposes to deliver messenger RNA (mRNA) coding BMPs (Bone morphogenetic proteins) as an innovative alternative to protein therapy or gene therapy for bone tissue regeneration (mRNA therapeutics delivery). The overall objective of the project is to formulate mRNA-lipid vector-hydrogel composite matrices (CreaBone) allowing a safe, local and transient expression of BMP dimers by host progenitor cells and to validate their therapeutic efficacy for bone regeneration..

ANR New funding by ANR for IMAGIN

Scientists from RMeS (REGOS Team), based at the University of Angers are pleased to announce the recent funding of the IMAGIN proposal as an ANR collaborative research. This project is based on the recent work of the group of Prof C. Ruckebusch (University of Lille) on chemical unmixing of spectral images combined to sparse sampling approach developed in the group of Prof N. Dobigeon (University of Toulouse). A new approach of sparse sampling, based on machine learning in chemical imaging, will be developed by Prof. D. Rousseau (University of Angers). Scientists from RMeS,  will be involved in developing a model of bone pathology with alteration of the chemical signature of bone. If successful, this approach should pave the way for the investigation of bone material properties in situ without having access to bone biopsies but also in a rapid acquisition that could be translated to clinical practice.

Seminars

Rémy Cochereau

Semi-permeable vesicles produced by microfluidics to tune the phase behaviour of encapsulated macromolecules

INRAE Nnantes
December 7, 2020, 10h00 - Via Zoom

RMeS in the spotlight

Régénérer le squelette : un biocomposite répare les pertes osseuses

Interview of P. Weiss

Sciences et Vie -

Les cellules souches porteuses d'espoir dans les lésions dégénératives

Interview of J. Guicheux

Le Quotidien du Médecin Mai 2020 -

New members

Lily Paillat Lily Paillat

Lily, who defended her PhD in July, returns as an engineer in the unit. She will be conducting cytotoxicity studies on CaP particles doped or not with Galium and cellular behaviour on and in hydrogel/CaP composites as part of the ImplantNano program.

She will join our unit in October 2021
Her supervisor will be Pierre Weiss

Maylis Girraudeau Maylis Giraudeau

Maylis Giraudeau is an engineer, she will be responsible for making mechanical characterizations of 3D materials and constructions, as part of the development of organo-mineral bio-ink for 3D printing.

She joined our unit on September 27th 2021
Her supervisors is Pierre Weiss

Asli Aslihan Argun

Aslihan is a postdoc in  Le Mans (supervised by E. NICOL) and she will develop an original transversal platform to promote angiogenesis and neovascularization by coculturing different type of cells in separated phases of biphasic hydrogels.

She will join our unit on October 1st 2021
Her supervisors are Pierre Weiss & Pierre Guihard

Marie Guicheteau Marie Guicheteau

Marie is a PhD student. She will evaluate the hypothesis that the SLC20A2/PiT2 protein can control variations in the volume of adipose and bone tissues and be involved in the deregulation of energy metabolism in pathology.

She joined our unit on September 1st 2021
Her supervisors are Sarah Beck-Cormier and Laurent Beck

Lucie Danet Lucie Danet

Lucie is M2 student. She will work on the role of the anti-aging protein α-Klotho.

She joined our unit on September 1st 2021
Her supervisor is Claire Vinatier

PhD defense & HDR

nora bouhsina Congratulations to Nora Bouhsina for her PhD Defense !

Nora defended her thesis on September 21th, 2021 at 2.00 pm (Amphi Ricordeau)

Contribution au développement de nouvelles techniques d’imagerie pour la détection précoce de la dégénérescence discale dans un contexte de médecine régénératrice

Directeur de thèse: Johann Clouet - Co-directeur : Marion Fusellier

Gildas Rethoré HDR of Gildas Rethoré

Gildas will defend his HDR on December 7th, 2021 at 2.00 pm

 

And among other things...



Retirement of Martial Masson
November 30th, 2020
 



RMeS General Assemby (Campus Gavy - St Nazaire) -
May 14th, 2018
 


Christmas Party RMeS ! December 18th, 2017