Int J of Hygiene
In vitro cytotoxic effects of secondary metabolites of DEHP and its alternative plasticizers DINCH and DINP on a L929 cell line

Eljezi T, Pinta P, Nativel F, Richard D, Pinguet J, Roy O, Sautou V, Grimandi G, Moreau E

Int J Hyg Environ Health. 2019 Apr;222(3):583-589 - Download full text

In vitro and in vivo evaluation of an electrospun-aligned microfibrous implant for Annulus fibrosus repair

Gluais M, Clouet J, Fusellier M, Decante C, Moraru C, Dutilleul M, Veziers J, Lesoeur J, Dumas D, Abadie J, Hamel A, Bord E, Chew SY, Guicheux J, Le Visage C

Biomaterials. 2019 Jun;205:81-93 - Download full text

Advanced Healthcare
Optimized Bioactive Glass: the Quest for the Bony Graft

Granel H, Bossard C, Nucke L, Wauquier F, Rochefort GY, Guicheux J, Jallot E, Lao J, Wittrant Y

Adv Healthc Mater. 2019 Apr 3:e1801542

Materials Science
Synthesis of calcium-deficient hydroxyapatite nanowires and nanotubes performed by template-assisted electrodeposition

Beaufils S, Rouillon T, Millet P, Le Bideau J, Weiss P, Chopart JP, Daltin AL

Mater Sci Eng C Mater Biol Appl. 2019 May;98:333-346 - Download full text


Fondation de l'avenirNew funding of Fondation de l'Avenir

Fondation de l'Avenir and his partner CDC Mutuelle have decided to fund our project entitled "Intra-articular injection of mesenchymal stem cells: evaluation in a humanized model of surgically induced osteoarthritis", headed by Prof. C. Le Visage. As a part of this new collaboration, they visited our lab on Feb. 22 and had discussion with the team involved in this project". Article...

nextI-site NExT Award for Vianney Delplace

Recently awarded a postdoctoral fellowship by the French Foundation for Medical Research (FRM), Vianney Delplace has obtained a 3-year financial support of 500 K€ from the i-site NExT (Nantes Excellence Trajectory) program, as a « junior talent ». Starting his own group within the RMeS Lab (INSERM 1229), Vianney will develop innovative hydrogel-based strategies for cartilage repair. Welcome on board, Vianney!

Leslie AwardBioregate Award for Leslie Frapin

Congratulations to Leslie Frapin who obtained the Bioregate Award for the best oral presentation "Young Researcher" for her talk entitled : "Controlled release of biological factors for progenitor cell-mediated endogenous repair of intervertebral discs".

Prix Fondation ArthroseTilman Award for Benoit Métayer

Congratulations to Benoit Metayer who obtained the Osteoarthritis Foundation Tilman Award for his work entitled : "Development of an osteoarthritis model in humanized mice to study the therapeutic effects of encapsulated human mesenchymal stem cells".

Workshops & symposia

Termis Meeting, 27th-31st May 2019, Rhodes, Greece

Several members of our unit organize symposia during this conference :

  • Vianney Delplace & Pierre Weiss : "From innovative hydrogel chemistry to musculoskeletal regeneration approaches"
  • Catherine Le Visage & Valérie Geoffroy: "MSC-derived Extracellular Vesicles: from production, engineering and administration challenges to bone tissue regenerative therapies"
  • Jérome Guicheux & Marianna Trifonnidou: Advanced therapies of the future for spinal regeneration: The H2020 European iPSpine project
  • Claire Vinatier & Anne Desrieux : "New frontiers in osteoarthritis treatment: prospects for stem cells, extracellular vesicles and biomaterials-assisted cell therapies"


Dominique PiolettiDominique Pioletti, PhD

The role of dissipation in developing hydrogels with increased mechanical and mechanobiological properties

Laboratory of Biomechanical Orthopedics,EPFL
April 24th, 2019, 11h00 - Amphi Ricordeau (Dental Faculty)


Guillaume MabilleauGuillaume Mabilleau, PhD

Gut hormones and bone quality

March 19th, 2019, 11h00 - Amphi Ricordeau (Dental Faculty)


New members

Caroline ChariauCaroline Chariau

Caroline (ass. ing. ) will work on Notochordal differentiation and stem cell-based therapy for intervertebral disc degeneration (H2020 iPSpine project; agreement No 825925)

She joined our unit on March 11th 2019
Her supervisor is Anne Camus

Nicolas VedrenneNicolas Védrenne

Nicolas is post-doctoral researcher
He will work on Notochordal differentiation and stem cell-based therapy for intervertebral disc degeneration (H2020 iPSpine project)

He joined our unit on March 11th 2019
His supervisor is Anne Camus

HassanHassan Kaafarani

Hassan is a M2 student.
He will work on REGOMIR project

He joined our unit on Feb. 20th 2019
His supervisor is Valérie Geoffroy

Pierre-Guillaume PiriouPierre-Guillaume Piriou

Pierre-Guillaume is a M2 student.
He will work on the evaluation of the biomechanical characteristics of coronary stents and their performance in simple model and bifurcation model.

He joined our unit on Jan. 28th 2019
His supervisors are Thierry Rouillon & Fabienne Jordana

PhD defense & HDR

KillianPhD Defense of Killian Flégeau

Killian will defend his thesis on April 24, 2019, at 14.00 pm

Développement et caractérisation d'hydrogels d'acide hyaluronique auto-réticulants injectables en ingénierie tissulaire du squelette

Directeur de thèse: P. Weiss - Co-directeur : Hélène Gautier

Maude GluaisPhD Defense of Maude Gluais

Maude Gluais defended her thesis on December 18, 2018, at 14.00 pm

Mise au point et évaluation de biomatériaux électrospinés pour la régénération de l’Annulus fibrosus

Directeur de thèse: C. Le Visage- Co-directeurs : J. Guicheux/J. Clouet. Congratulations Maude !

Amadou TourePhD Defense of Amadou Toure

Amadou Toure defended his thesis on December 19, 2018, at 9.30 am

Contribution au développement de substituts osseux auto-réticulants en ingénierie tissulaire osseuse maxillo-faciale

Directeur de thèse: P. Weiss - Co-directeur : B. Giumelli. Congratulations Amadou !

And among other things...

General Assembly 2018
RMeS General Assemby (Campus Gavy - St Nazaire) -
May 14th, 2018

Photo Fête de Noël
Christmas Party RMeS ! December 18th, 2017

Olympiades RMES

The 2nd Edition of the RMeS "Olympiades" has taken place on Sept. 18th, 2017. 4 teams have met in good spirits. Thanks to all the participants!